Thursday, January 5, 2023

According to a study, your blood type could indicate your chance of suffering a stroke before age 60

 1. What your blood type tells you about your risk of having a stroke 

According to a new study, your blood type can tell you if you are likely to have a stroke early on. The blood supply to a portion of the brain is disrupted or reduced during an ischemic stroke, preventing brain tissue from receiving oxygen and nutrients. In a matter of minutes, brain cells may die as a result.

New methods for predicting and preventing strokes in young adults could be developed thanks to these findings. The paper's findings were published in the journal Neurology.

2. What blood types exist?

The term "blood types" refers to the classification of blood based on the presence or absence of a wide variety of chemicals on the surface of red blood cells, such as antibodies and inherited antigenic substances. A person's blood group is determined by the genes they inherit from their parents. There are four main blood groups: A, B, AB, and O.

3.About the study 

The researchers looked at 48 studies from Asia, Europe, and North America on genetics and ischemic stroke. These included 576,353 people who did not have a stroke and 16,927 people who had a stroke.

5,825 individuals had early onset stroke, which was defined as an ischemic stroke that occurred before the age of 60. There were 9,269 cases of late onset stroke, which occurred in people over the age of 60.

4. Who is more vulnerable?

The researchers found that people with type A blood are more likely to have a stroke before the age of 60 than people with other blood types. The gene for the A1 subgroup and early-onset stroke have been clearly linked through genomic research, the researchers noted.

5. Why is the risk greater for blood type A?

"The reason why blood type A would increase the risk remains a mystery. However, senior author and University of Maryland vascular neurologist Steven Kittner said, "It probably has something to do with blood-clotting factors like platelets and cells that line the blood vessels as well as other circulating proteins, all of which play a role in the development of blood clots."

“In particular, our meta-analysis suggests that nearly all of the genetic variants associated with early stroke are linked to blood types A and O. The study's lead author, Braxton D. Mitchell, PhD, MPH, of the University of Maryland School of Medicine in Baltimore, added, "These gene variants may increase a person's risk of developing blood clots, which can result in stroke."

They also mentioned that stroke risk was 12% lower in people with blood type O than in people with other blood types.

6. No need for additional testing or monitoring

 The researchers found that compared to people with other blood types, people whose genomes coded for a variation of the A blood group had a 16% higher risk of having a stroke before the age of 60.

However, the researchers stated that there is no need for additional screening or monitoring because the risk of stroke among people with type A blood is minimal.

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